| Assertion (A): | Immune response gradually decreases with age | 
| Reason (R): | One of the factors is degeneration of thymus gland with ageing | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Ketonuria and glycosuria are the characteristic symptoms of diabetes insipidus | 
| Reason (R): | Diabetes insipidus is caused due to deficiency of insulin | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Estrogen shows its effects by regulating the gene expression in its target organs | 
| Reason (R): | Estrogen being a steroid hormone interacts with its intracellular receptors and its hormone receptor complex interacts with cellular genome | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Hormone such as cortisol directly acts on nuclear DNA of target cells through intracellular receptor | 
| Reason (R): | Steroid based hormones can cross the amphipathic lipid bilayer | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Addison's disease and Cushing's disorder result from deficiency of hormones secreted by adrenal medulla | 
| Reason (R): | Patients suffering from these experience low blood sugar level, high Na+ and low K+ in plasma | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Hypothalamus is connected to the posterior lobe of the pituitary by hypophyseal portal veins | 
| Reason (R): | The hypophyseal portal arteries carry blood from the hypothalamus to the neurohypophysis | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Atrial natriuretic factor (ANF) is secreted by the wall of heart's atria | 
| Reason (R): | ANF is secreted when there is a decrease in blood flow to the heart | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Diabetes mellitus is a hypothalamic disorder | 
| Reason (R): | Low blood glucose level and cholesterol level cause diabetes mellitus | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Secretin stimulates release of pancreatic enzymes, water and bicarbonate ions from liver and pancreas | 
| Reason (R): | It acts majorly both on exocrine and endocrine parts of pancreas and liver | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. | 
| Assertion (A): | Melatonin secretion is high at night and low during the day | 
| Reason (R): | Tryptophan is a non-essential amino acid | 
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). | 
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). | 
| 3. | (A) is true but (R) is false. | 
| 4. | Both (A) and (R) are false. |