Statement-I: Non-homologous DNA will attach to a DNA probe. 
Statement-II: At high temperature, two complementary DNA strands will anneal. 

1. Only statement - I is true
2. Only statement - II is true 
3. Both statements - I and II are true
4. Both statements - I and II are false

Subtopic:  Molecular Diagnosis |
Level 3: 35%-60%
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Match the following :-

Column-I Column-II
I. Biopiracy (A)  Gene therapy
II.   Retroviral vector materials   (B)   Illegal removal of biological    
III. Biopatent entities (C) Right granted for biological
IV.   Kohler and Milstein         (D)  Monoclonal antibody

1. I - B, II - A, III - D, IV - C

2. I - B, II - A, III - C, IV - D

3. I - B, II - C, III - A, IV - D

4. I - D, II - A, III - B, IV - C

Subtopic:  Gene Therapy | Ethical Issues |
 85%
Level 1: 80%+
Hints

Match the following :-

Column-I

Column-II

I. Escherichia coli

(A) Nif gene

II. Bacillus thuringiensis

(B) Interferon

III. Rhizobium meliloti

(C) Bt toxin

IV. Pseudomonas putida

(D) Bioremediation

(1) I - B, II - A, III - D, IV - C

(2) I - B, II - A, III - C, IV - D

(3) I - B, II - C, III - A, IV - D

(4) I - D, II - A, III - B, IV - C

Subtopic:  Bt Crops | Transgenic Microbes & Animals |
 90%
Level 1: 80%+
Hints

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3. In a type of yeast fermentation , the entire medium with fermenting organism is removed from the bioreactor after reaching an alcohol level of 10-12%. This process is called
a. Continuous process
b. Batch process
c. Synchronous culture
d. Immobilized process

Subtopic:  Large Scale Production: II | Large Scale Production |
 64%
Level 2: 60%+
Hints

The immobilization of enzymes is achieved by
a. Killing the cells without affecting enzymes
b. Attaching the enzymes covalently to a solid support
c. Entrapping the living cells in gel
d. All of these

 75%
Level 2: 60%+
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A genetically engineered micro-organism which has found extensive use in bioremediation oil spills is a species of
1. Trichoderma
2. Mucuna
3. Pseudomonas
4. Bacillus

Subtopic:  Transgenic Microbes & Animals |
 77%
Level 2: 60%+
Hints

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Incorporation of the gene for phytoene synthase and carotene desaturase to make a particular variety of yellowish rice has proven useful in the treatment of-

1. Congenital heart disease
2. Night blindness
3. Xeroderma
4. Phrenoderma
Subtopic:  Other GM Crops |
 91%
Level 1: 80%+
Hints

Cry toxin acts by

1. Lysis of intestinal cells
2. Binding to midgut epithelium
3. Cell swelling
4. More than one correct
Subtopic:  Bt Crops |
 81%
Level 1: 80%+
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Humulin production through microbial factories does not include the incorporation of the gene for

1. A peptide 2. B peptide
3. C peptide 4. Both (1) and (2)
Subtopic:  Med Applications & Humulin |
 87%
Level 1: 80%+
Hints

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What is true for molecular diagnosis?

1. It is inexpensive
2. It involves drawing of serum for the test
3. It can be used in the initial stages of the onset of the disease
4. All of the above
Subtopic:  Molecular Diagnosis |
 52%
Level 3: 35%-60%
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