| 1. | undergoes oxidative decarboxylation in cytosol itself by a complex set of reactions catalysed by pyruvic kinase. |
| 2. | undergoes reduction in cytosol itself by a complex set of reactions catalysed by pyruvic dehydrogenase. |
| 3. | undergoes oxidative decarboxylation in mitochondrial matrix by a complex set of reactions catalysed by pyruvic dehydrogenase. |
| 4. | undergoes oxidative phosphorylation in mitochondrial matrix by a complex set of reactions catalysed by pyruvic decarboxylase. |
| 1. | within the inner mitochondrial membrane |
| 2. | on the outer surface of the inner mitochondrial membrane |
| 3. | on the inner surface of the inner mitochondrial membrane |
| 4. | in the mitochondrial matrix |
| 1. | 3 and 2 respectively | 2. | 2 and 3 respectively |
| 3. | 1 and 2 respectively | 4. | 2 and 1 respectively |
| I: | The F1 headpiece is a peripheral membrane protein complex and contains the site for synthesis of ATP from ADP and inorganic phosphate. |
| II: | F0 is an integral membrane protein complex that forms the channel through which protons cross the inner membrane. |
| III: | The F0 headpiece is a peripheral membrane protein complex and contains the site for synthesis of ATP from ADP and inorganic phosphate. |
| IV: | F1 is an integral membrane protein complex that forms the channel through which protons cross the inner membrane. |
| Assertion (A): | It is possible to make calculations of the net gain of ATP for every glucose molecule oxidised; but in reality this can remain only a theoretical exercise. |
| Reason (R): | These calculations can be made only on certain assumptions that are not really valid in a living system. |
| 1. | Both (A) and (R) are True and (R) correctly explains the (A) |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of the (A) |
| 3. | (A) is True but (R) is False |
| 4. | (A) is False but (R) is True |