Assertion (A): Insulin is not administered orally.
Reason (R): Insulin gets digested in the stomach before being absorbed into the blood.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.

Subtopic:  Pancreas |
 76%
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Assertion (A): The physiological functions of target tissue are regulated by hormones.
Reason (R): The hormone-receptors complexes formation leads to certain biochemical changes in the target tissue.
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Mechanism of Hormone Action |
 81%
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Assertion (A): The hormones which interact with membrane  bound receptors normally do not enter the target cell.
Reason (R): These hormones generate second messengers which in turn regulate the cellular metabolism. 
1. Both (A) and (R) are true and (R) is the correct explanation of (A).
2. Both (A) and (R) are true but (R) is not the correct explanation of (A).
3. (A) is true but (R) is false.
4. Both (A) and (R) are false.
Subtopic:  Mechanism of Hormone Action |
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Suppose you were working in a diagnostic laboratory and had measured high levels of glucagon and low levels of insulin in a blood sample from a patient. What would be the most likely explanation?
1. The patient had consumed a large soft drink on the way to the lab
2. The patient was suffering from diabetes
3. The patient had not eaten anything for several hours
4. You had made an error in one or both of the measurements 
Subtopic:  Pancreas |
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A scientist develops a drug that she thinks might inhibit the release of gonadotrophin-releasing hormone (GnRH) from the hypothalamus. Some volunteer female subjects take the drug. Which of the following results obtained from the volunteers would support the scientist hypothesis?
1. Increased levels of oestrogen in the blood
2. Earlier onset on menstruation
3. Follicle development
4. Decreased levels of luteinizing hormone (LH) in the blood
 
Subtopic:  Adenohypophysis & Hypothalamus |
 73%
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The secretion of a less than normal amount of the hormone gastrin would have which effect?
1. Stomach pH would decrease
2. Protein digestion in the stomach would decrease
3. Secretion of alkaline mucus in the stomach would increase 
4. Carbohydrate digestion in the stomach would increase 
Subtopic:  Misc. Hormones |
 65%
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Some atheletes take steroids in an attempt to enhance their physical performance. This can lead to decreased sperm production and even sterility. What is the most likely explanation for this effect?
1. Increased stimulation of anterior pituitary to produce LH
2. Excessive growth of testicular tissue
3. Suppression of the natural production of thyroxine due to the destruction of thyroid tissue
4. Interference in the proper negative feedback control of testosterone
 
Subtopic:  Misc. Hormones |
 65%
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If you were outside for a long time on a hot, dry day, without anything to drink, which of the following would happen?
1. The osmotic pressure of your blood would decrease
2. The production of thyroxine by your thyroid gland would increase
3. The secretion of ADH from your pituitary gland would increase 
4. The reabsorption of fluids from your kidney tubules would decrease 
Subtopic:  Adenohypophysis & Hypothalamus |
 75%
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In a hormonal control system, hormone A inhibits the secretion of substance B. If this system works by positive feedback, which of the following would be correct?
1. Levels of B will stabilize at a moderate level
2. Substance B stimulates the production of hormone A
3. Secretion of substance B should stop completely 
4. Levels of hormone A should not be affected by the levels of substance B
Subtopic:  Mechanism of Hormone Action |
 57%
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A scientist develops a new drug, and finds that when it is administered in human there is a substantial increase in the volume of urine produced. When he administers ADH/vasopressin at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:
1. Blocks the receptors for ADH on the collecting tubules of the kidney
2. Blocks the release of ADH from the pituitary
3. Mimics the action of ADH
4. Decrease blood pressure 
Subtopic:  Adenohypophysis & Hypothalamus |
 56%
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