Sickle cell anaemia results from.
1. A chromosomal aberration
2. Non disjunction of autosome
3. A point mutation
4. Blood transfusion reaction
Identify the incorrect statement:
(1) In addition to recombination, mutation is another phenomeonon that leads to variation in DNA.
(2) Chromosomal aberrations are commonly observed in cancer cells.
(3) A classical example of a point mutation is sickle cell anaemia.
(4) Non ionising radiations cannot be mutations.
Given below is the initial amino acids of the beta chain of a hemoglobin molecule. What will be true about this hemoglobin molecule ?
1. | The RBCs carrying this molecule will undergo sickling at high oxygen tension |
2. | The RBCs carrying this molecules will undergo sickling at low oxygen tension |
3. | There will be a quantitative decrease in the synthesis of this molecule |
4. | This is normal beta chain of the hemoglobin molecule |
Sickle cell anaemia has not been eliminated from the African population because :
(1) it is controlled by recessive genes
(b) it is not a fatal disease
(3) it provides immunity against malaria
(4) it is controlled by a dominant genes
Sickle cell anaemia is example of
(1) sex-linked inheritance
(2) deficiency disease
(3) autosomal heritable disease
(4) infectious disease