In which disorder, change of single base pair in the gene for beta globin chain results in change of glutamic acid to valine?
1. Thalassemia 2. Sickle cell anemia
3. Haemophilia 4. Phenylketonuria
Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 85%
Level 1: 80%+
NEET - 2023
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 Select the correct statements about sickle cell anemia:
A: There is a change in the gene for beta-globin
B: In beta-globin, there is a valine in place of Lysine
C: It is an example of point mutation
D: In the normal gene, U is replaced by A

Choose the correct answer from the options given below:
1. (B), (C) and (D) only 2. (B) and (D) only
3. (A), (B) and (D) only 4. (A) and (C) only
Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 83%
Level 1: 80%+
NEET - 2023
Hints

In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased?

1. 25% 2. 100%
3. 50% 4. 75%
Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 58%
Level 3: 35%-60%
NEET - 2021
Hints

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Select the correct match:

1. Phenylketonuria Autosomal dominant trait
2. Sickle cell anemia Autosomal recessive trait chromosome - 11
3. Thalassemia X linked
4. Haemophilia Y linked

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 69%
Level 2: 60%+
NEET - 2020
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