| 1. | Thalassemia | 2. | Sickle cell anemia |
| 3. | Haemophilia | 4. | Phenylketonuria |
| A: | There is a change in the gene for beta-globin |
| B: | In beta-globin, there is a valine in place of Lysine |
| C: | It is an example of point mutation |
| D: | In the normal gene, U is replaced by A |
| 1. | (B), (C) and (D) only | 2. | (B) and (D) only |
| 3. | (A), (B) and (D) only | 4. | (A) and (C) only |
In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased?
| 1. | 25% | 2. | 100% |
| 3. | 50% | 4. | 75% |
Select the correct match:
| 1. | Phenylketonuria | Autosomal dominant trait |
| 2. | Sickle cell anemia | Autosomal recessive trait chromosome - 11 |
| 3. | Thalassemia | X linked |
| 4. | Haemophilia | Y linked |