The tendency of the population to remain in genetic equilibrium may be disturbed by:
| 1. | lack of migration | 2. | lack of mutations | 
| 3. | lack of random mating | 4. | random mating | 
The loss of genetic variation that occurs when a new population is established by a very small number of individuals from a larger population is called as:
| 1. | the bottleneck effect | 2. | the founder effect | 
| 3. | assortative mating | 4. | random mating | 
At a particular locus, the 'A' allele frequency is 0.6 and that of 'a' allele is 0.4. What would be the frequency of heterozygotes in a random mating population at equilibrium? 
| 1. | 0.24 | 2. | 0.16 | 
| 3. | 0.48 | 4. | 0.34 | 
In some African populations, the frequency of the sickle cell allele in the human population is much higher than normal. This can be an example of:
| 1. | gene flow | 2. | heterozygote advantage | 
| 3. | genetic drift | 4. | nonrandom mating | 
A population will not exist in Hardy-Weinberg equilibrium if: