All the following are examples of competitive enzyme inhibition except:
| 1. | Sulfa drugs used as antibacterial agents |
| 2. | Ethyl alcohol used in methyl alcohol poisoning |
| 3. | Malonate inhibiting succinic dehydrogenase enzyme |
| 4. | Glucose 6 phosphate inhibiting hexokinase in brain |
Select the option which is not correct with respect to enzyme action:
| 1. | Substrate binds with enzyme at its active site. |
| 2. | Addition of a lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate. |
| 3. | A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate. |
| 4. | Malonate is a competitive inhibitor of succinic dehydrogenase. |

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Consider the given two statements:
| I: | In competitive enzyme inhibition, the substrate and inhibitor cannot bind to the enzyme at the same time. |
| II: | The inhibitor always has a much higher affinity for the active site than the normal substrate. |
| 1. | Both I and II are correct and II explains I |
| 2. | Both I and II are correct but II does not explain I |
| 3. | I is correct but II is incorrect |
| 4. | I is incorrect but II is correct |