Q. No.| A. | This disorder was first described by Langdon Down (1866). |
| B. | Such an individual has overall masculine development. However, the feminine development is also expressed. |
| C. | The affected individual is short statured. |
| D. | Physical, psychomotor and mental development is retarded. |
| E. | Such individuals are sterile. |
| 1. | A and E only | 2. | A and B only |
| 3. | C and D only | 4. | B and E only |
| 1. | Thalassemia | 2. | Down's syndrome |
| 3. | Turner's syndrome | 4. | Klinefelter's syndrome |
Match List-I with List-II
| List-I | List-II | ||
| (a) | Haemophilia | (i) | Inborn error of metabolism which lacks an enzyme that converts phenylalanine into tyrosine |
| (b) | Down's Syndrome | (ii) | Sex-linked recessive disorder; a defect in blood coagulation |
| (c) | Phenylketonuria | (iii) | Presence of additional copy of X-chromosome (44+XXY) |
| (d) | Klinefelter's Syndrome | (iv) | Additional copy of chromosome number 21 |
Choose the correct answer from the options given below:
| (a) | (b) | (c) | (d) | |
| 1. | (ii) | (iv) | (i) | (iii) |
| 2. | (iv) | (ii) | (i) | (iii) |
| 3. | (ii) | (iii) | (i) | (iv) |
| 4 | (i) | (ii) | (iii) | (iv) |
1. 47 chromosomes with XXY sex chromosomes
2. 45 chromosomes with XO sex chromosomes
3. 47 chromosomes with XYY sex chromosomes
4. Trisomy of chromosome 21
| I: | Haemophilia is a sex-linked recessive disease. |
| II: | Down’s syndrome is due to aneuploidy. |
| III: | Phenylketonuria is an autosomal recessive gene disorder. |
| IV: | Sickle cell anaemia is an X-linked recessive gene disorder |
2. I, III and IV are correct
3. I, II and III are correct
4. I and IV are correct
A cell at the telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at the telophase stage. There is no formation of a cell plate and thus the cell is containing more chromosomes as compared to other dividing cells. This would result in:
1. polyploidy
2. somaclonal variation
3. polyteny
4. aneuploidy
A woman with 47 chromosomes, due to three copies of chromosome 21, is characterized by:
| 1. | Turner syndrome | 2. | Down syndrome |
| 3. | Superfemaleness | 4. | Triploidy |
Which of the following is the correct match:
1. Down Syndrome = 21st Chromosome
2. Sickel cell anaemia = X – Chromosome
3. Haemophilia = Y – Chromosome
4. Parkinson Disease = X & Y Chromosomes
Mangolian idiots are due to trisomy in the 21st chromosome is called:
1. Down's syndrome
2. Turner's syndrome
3. Kleinfelters syndrome
4. Triplex syndrome
Reason for trisomy in Down's syndrome is:
1. Non-disjunction during sperm formation
2. Non-disjunction during egg formation
3. Non-disjunction at the time of egg or sperm formation
4. Addition of one extra chromosome during mitosis
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