Select the correct statements regarding mechanism of muscle contraction.
A. It is initiated by a signal sent by CNS via sensory neuron.
B. Neurotransmitter generates action potential in the sarcolemma.
C. Increased Ca++ level leads to the binding of calcium with troponin actin filaments.
D. Masking of active site for actin is activated.
E. Utilising the energy from ATP hydrolysis to form cross bridge.
Choose the most appropriate answer from the options given below:
1. BC and E only
2. CD and E only
3. A and D only
4. BD and E only
Subtopic:  Sliding Filament Theory | Muscle Contraction: Other Considerations |
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Calcium is important in skeletal muscle contraction because it:
1. binds to troponin to remove the masking of active sites on actin for myosin.
2. activates the myosin ATPase by binding to it.
3. detaches the myosin head from the actin filament.
4. prevents the formation of bonds between the myosin cross bridges and the actin filament.
Subtopic:  Excitation Contraction Coupling I | Sliding Filament Theory | Muscle Contraction: Other Considerations |
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Stimulation of a muscle fiber by a motor neuron occurs at:

1. the neuromuscular junction

2. the transverse tubules

3. the myofibril

4. the sarcoplasmic reticulum

Subtopic:  Muscle Contraction: Other Considerations |
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