| Assertion (A): | Hb cannot get saturated with O2 more than 70%. |
| Reason (R): | The affinity O2 to Hb increases with the rise of pCO2. |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
| 3. | (A) is True but (R) is False. |
| 4. | Both (A) and (R) are False. |
| Assertion (A): | \(O_2\) binds with Hb in an irreversible manner. |
| Reason (R): | \(CO_2\) combines with Hb both is an irreversible and reversible manner. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion (A): | In the alveoli, where there is high pO2, low pCO2, lesser H+ concentration and lower temperature, the factors are all favourable for the formation of oxyhemoglobin. |
| Reason (R): | Every 100 mL of oxygenated blood deliver around 2.5 mL of O2 to the tissues normally. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion (A): | CO2 is carried by Hb as carbaminohaemoglobin (about 20-25%). |
| Reason (R): | When pCO2, is high and pO2 is low as in tissues, more binding of CO2 to Hb occurs. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Column - I | Column - II |
| A. Carboxyhaemoglobin | i. O2 |
| B. Carbaminohaemoglobin | ii. NO-3 |
| C. Methaemoglobin | iii. CO2 |
| D. Oxyhaemoglobin | iv. CO |
| 1. | All the factors that shift the oxygen haemoglobin dissociation curve to the right increase Bohr effect |
| 2. | The overall result of Bohr effect is to allow greater O2 transport from lungs to tissues |
| 3. | Increase in CO2 concentration in the blood results in increased dissociation of oxyhaemoglobin |
| 4. | More than one option is correct |
| i. | The approximate ratio of residual volume and total lung capacity is 1 : 5 |
| ii. | Haldane effect describes the dissociation of CO2 from Hb and facilitates its release into alveoli due to oxygenation of Hb |
| iii. | Maximum CO2 is carried in the blood as NaHCO3 |
| iv. | When a plain dweller move to high altitudes (3,500 m or more), he/she will have increase in RBC production and decreased breathing rate |
| v. | Under certain conditions, the P50 value of Hb rises, due to this the affinity of Hb of combining with O2 rises. |
| 1. | Two | 2. | Three |
| 3. | One | 4. | Four |