Queen Victoria of England was :

1. Haemophilic carrier

2. Colour blind 

3. AIDS patients 

4. Deaf 

Subtopic:  Mendelian Disorders: Hemophilia |
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Which of the following amino acid substitution in the beta chain of the haemoglobin molecule leads to the development of sickle cell anaemia?
1. Arginine by tyrosine                  2. Tyrosine by phenylalanine
3. Valine by Glutamic acid             4. Glutamic acid by Valine

Subtopic:  Mendelian Disorders: Hemophilia |
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The incorrect statement with regard to haemophilia is

(1) it is a sex-linked disease

(2) it is a recessive disease

(3) it is a dominant disease

(4) a single protein involved in the clotting of blood effected

Subtopic:  Mendelian Disorders: Hemophilia |
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The genetic disease that transfer from a phenotypically normal but carrier female to only some of the male progenies. The disease is

1. Autosomal dominant

2. Autosomal recessive

3. Sex-linked dominant

4. Sex-linked recessive

Subtopic:  Mendelian Disorders: Hemophilia |
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What is incorrect for Hemophilia?

1. In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected.

2. In an affected indlvidual a simple cut will result in non-stop bleeding.

3. The heterozygous female (carrier) for haemophilia may transmit the disease to sons.

4. The possibility of a female becoming a haemophilic is extremely rare because mother of such a female has to be hemophilic and the father should be a carrier.

Subtopic:  Mendelian Disorders: Hemophilia |
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Match the following

   Column-l                       Column-ll

a.  Haemophilia               i.  Rudimentary ovaries

b.  Sickle cell anaemia     ii.  X-linked recessive

c.  Turner's syndrome      iii.  Gynaecosmastia

d.  Klinefelter's                iv.  Autosomal recessive 
     syndrom

a.  a(ii), b(iv), c(i), d(iii)

b.  a(ii), b(iv), c(iii), d(i)

c.  a(iv), b(ii), c(i), d(iii)

d.  a(iv), b(i), c(ii), d(iii) 

Subtopic:  Mendelian Disorders: Sickle Cell Anemia | Mendelian Disorders: Hemophilia | Sex Aneuploidy - Turner & Klinefelter Syndrome |
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