The first clinical gene therapy was done for the treatment of
| 1. | AIDS | 
| 2. | Cancer | 
| 3. | Cystic fibrosis | 
| 4. | SCID (Severe Combined Immuno Deficiency resulting from the deficiency of ADA | 
 
The SCID patient has a defective gene for the enzyme Adenosine Deaminase (ADA) due to which he/she lacks functional T-lymphocytes and therefore, fails to fight the infecting pathogen.
 
                    
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