A narrow-spectrum antibiotic is active against-
| 1. | Gram-positive or gram-negative bacteria. | 
| 2. | Gram-negative bacteria only. | 
| 3. | Single organism or one disease. | 
| 4. | Both gram-positive and gram-negative bacteria. | 
Broad-spectrum antibiotics are effective against several different types of harmful bacteria i.e., a wide range of gram-positive and gram-negative bacteria.
These effective mainly against gram-positive or gram-negative bacteria are narrow-spectrum antibiotics.
Chloramphenicol is a broad-spectrum antibiotic and penicillin-G that has a narrow spectrum. If an antibiotic is effective against a single organism or disease then it is a limited spectrum antibiotic.
 
                    
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